谭彩萍的个人简介
谭彩萍，女，1981年03月出生，湖南省常德市人，中山大学化学与化学工程学院副教授。
人物经历
教育经历1998.9―2002.6华南师范大学化学与环境学院，学士；?
2002.9―2008.6中山大学化学与化学工程学院，博士。
工作经历2008.03―2011.03 ? 中山大学生命科学学院，博士后；?
2011.04―2016.1 中山大学化学与化学工程学院，讲师；
2016.1―至今 ?中山大学化学与化学工程学院，副教授。
讲授课程
本科生课程《无机化学》、《化学生物学综合实验》、《现代无机化学进展》、《基础化学实验》、《普通化学》。
研究方向
从事的学科领域为生物无机化学。研究兴趣包括靶向性金属抗肿瘤药物的设计、抗肿瘤活性及机制研究。近两年，以与肿瘤发生、发展的关键的蛋白分子为靶点，设计了系列的金属配合物作为新颖的抑制剂，并研究了它们的抗肿瘤作用机制。主要研究的靶点包括组蛋白去乙酰化酶（Histone deacetylases, HDACs）和细胞周期素依赖性激酶（Cyclin-dependent kinases, CDKs）等。
科研项目
1. 广东省“百千万工程青年拔尖人才”，2016.08-2019.08，10万元。?
2.高校基本科研业务费青年教师重点培育项目，2016.01-2017.12，30万元。?
3. 广东省自然科学基金（杰出青年基金），2015.08-2019.08，100万元。?
4. 国家自然科学基金（面上项目），2016.01-2019.12，77.6万元。?
5. 国家高技术研究发展计划(863计划)子课题，2012.01-2015.12，92.5万元。?
6. 国家自然科学基金 (青年科学基金项目)，2013.01-2015.012，25万元。?
7. 广州市科技计划项目，2014.01-2016.12，8万元。?
8. 高校基本科研业务费青年教师培育项目，2013.01-2015.12，10万元。?
9. 第四十四批中国博士后科学基金，2008.03-2010.03，3万元。?
论著一览
20171. Zhang, D. Y., Zheng, Y., Tan, C. P.*, Sun, J. H., Zhang, W., Ji, L. N. and Mao, Z. W.* Graphene Oxide Decorated with Ru(II)u2013Polyethylene Glycol Complex for Lysosome-Targeted Imaging and Photodynamic/Photothermal Therapy. ACS Applied Materials & Interfaces 2017 DOI: 10.1021/acsami.6b13808. IF: 7.145
2. Cao, J. J., Tan, C. P.*, Chen, M. H., Wu, N., Yao, D. Y., Liu, X. G., Ji, L.-N., Mao, Z. W.* Targeting cancer cell metabolism with mitochondria-immobilized phosphorescent cyclometalated iridium (III) complexes. Chemical Science 2017, 8, 631-640. IF: 9.144
3. Xue, S. S., Tan, C. P.*, Chen, M. H., Cao, J. J., Zhang, D. Y., Ye, R. R., Ji, L. N. and Mao, Z. W.* Tumor-targeted supramolecular nanoparticles self-assembled from a ruthenium-beta-cyclodextrin complex and an adamantane-functionalized peptide. Chemical Communications 2017, 53 (5), 842-845. IF: 6.567 (Front Cover)
2016
4. ?Wang, F. X., Chen, M. H., Hu, X. Y., Ye, R. R., Tan, C. P.*, Ji, L. N. and Mao, Z. W. Ester-Modified Cyclometalated Iridium(III) Complexes as Mitochondria-Targeting Anticancer Agents. Scientific Reports 2016, 6, 38954. IF: 5.228
5. Ye, R. R., Tan, C. P.*, Ji, L. N. and Mao, Z. W.* Coumarin-appended phosphorescent cyclometalated iridium(III) complexes as mitochondria-targeted theranostic anticancer agents. Dalton Transactions 2016, 45(33), 13042-13051. IF: 4.177 (Front Cover)
6. Ye, R. R., Tan, C. P.*, Chen, M. H., Hao, L., Ji, L. N. and Mao, Z. W.* Mono- and dinuclear phosphorescent rhenium(I) complexes: impact of subcellular localization on anticancer mechanisms. Chemistry-A European Journal 2016, 22(23), 7800-7809. IF: 5.771
7. Zhang, W., Shen, J., Su, H., Mu, G., Sun, J. H., Tan, C. P., Liang, X. J., Ji, L. N., Mao, Z. W.* Co-delivery of cisplatin prodrug and chlorin e6 by mesoporous silica nanoparticles for chemo-photodynamic combination therapy to combat drug resistance. ACS Applied Materials & Interfaces 2016, 8(21), 13332-13340. IF: 7.145
20158. He, L., Li, Y., Tan, C. P.*, Ye, R. R., Chen, M. H., Cao, J. J., Ji, L. N. and Mao, Z. W.* Cyclometalated iridium(III) complexes as lysosome-targeted photodynamic anticancer and real-time tracking agents. Chemical Science 2015, 6, 5409-5418. IF: 9.144 (Back Cover)
9. Ye, R. R., Tan, C. P.*, Lin, Y. N., Ji, L. N., Mao, Z. W.* A phosphorescent rhenium(I) histone deacetylase inhibitor: mitochondrial targeting and paraptosis induction. Chemical Communications 2015, 51(39),8353-8356. IF: 6.567
10. Li, Y., Tan, C. P. (Co-first author), He, L., Ji, L. N., Mao, Z. W.* Phosphorescent iridium(III)-bis-N-heterocyclic carbene complexes as mitochondria-targeted theranostic and photodynamic anticancer agents. Biomaterials 2015, 39, 95-104. IF: 8.387
11. Zhang, W., Li, Y., Sun, J. H., Tan, C. P., Ji, L. N., Mao, Z. W.* Supramolecular self-assembled nanoparticles for chemo-photodynamic dual therapy against cisplatin resistant cancer cells. Chemical Communications 2015, 51(10), 1807-1810. IF: 6.567
12. Li, J. M., Zhang, W., Su, H., Wang, Y. Y., Tan, C. P., Ji, L. N., Mao, Z. W.* Reversal of multidrug resistance in MCF-7/ADR cells by codelivery of doxorubicin and BCL2 siRNA using a folic acid-conjugated polyethylenimine hydroxypropyl-beta-cyclodextrin nanocarrier. International Journal of Nanomedicine 2015, 10, 3147-3162. IF: 4.32
201413. ?He, L., Tan, C. P.*, Ye, R. R., Zhao, Y. Z., Liu, Y. H., Zhao, Q., Ji, L. N., Mao, Z. W.* Theranostic iridium(III) complexes as one- and two-photon phosphorescent trackers to monitor autophagic lysosomes. Angewandte Chemie International Edition 2014, 53(45), 12137-12141. IF: 11.709
14. ?Ye, R. R., Tan, C. P.*, He, L., Chen, M. H., Ji, L. N., Mao, Z. W.* Cyclometalated Ir(III) complexes as targeted theranostic anticancer therapeutics: combining HDAC inhibition with photodynamic therapy. Chemical Communications 2014, 50(75), 10945-10948. IF: 6.567
15. ?He, L., Liao, S. Y., Tan, C. P.*, Lu, Y. Y., Xu, C. X., Ji, L. N., Mao, Z. W.* Cyclometalated iridium(III)-beta-carboline complexes as potent autophagy-inducing agents. Chemical Communications 2014, 50(42), 5611-5614. IF: 6.567
16. ?Tan, C. P., Lu, Y. Y., Ji, L. N., Mao, Z. W.* Metallomics insights into the programmed cell death induced by metal-based anticancer compounds. Metallomics 2014, 6(5), 978-995. IF: 3.54 (Front Cover)
17. ? Zhao, M. X., Zhao, M., Zeng, E. Z., Li, Y., Li, J. M., Cao, Q., Tan, C. P., Ji, L. N., Mao, Z. W.* Enhanced anti-cancer efficacy to cancer cells by doxorubicin loaded water-soluble amino acid-modified beta-cyclodextrin platinum complexes. Journal of Inorganic Biochemistry 2014, 137, 31-39. IF: 3.205
18. ? Li, Y., Liu, G. F.*, Tan, C. P., Ji, L. N., Mao, Z. W.* Antitumor properties and mechanisms of mitochondria-targeted Ag(I) and Au(I) complexes containing N-heterocyclic carbenes derived from cyclophanes. Metallomics 2014, 6(8), 1460-1468. IF: 3.54
201319. ?Ye, R. R., Ke, Z. F., Tan, C. P.*, He, L., Ji, L. N., Mao, Z. W.* Histone-deacetylase-targeted fluorescent ruthenium(II) polypyridyl complexes as potent anticancer agents. Chemistry-A European Journal 2013, 19(31), 10160-10169. IF: 5.771 (Front Cover)
20. ?He, L., Liao, S. Y., Tan, C. P.*, Ye, R. R., Xu, Y. W., Zhao, M., Ji, L. N., Mao, Z. W.* Ruthenium-arene-carboline complexes as potent inhibitors of cyclin-dependent kinase 1: synthesis, characterization and anticancer mechanism studies. Chemistry-A European Journal 2013, 19(36), 12152-12160. IF: 5.771
201221. ? Zheng, X. H., Zhong, Y. F., Tan, C. P., Ji, L. N., Mao, Z. W.* Pt(II) squares as selective and effective human telomeric G-quadruplex binders and potential cancer therapeutics. Dalton Transactions 2012, 41(38), 11807-11812. IF: 4.177
22. ? Wang, H. L., De Yonker, N. J., Gao, H., Tan, C. P., Zhang, X. T., Ji, L. N., Zhao, C. Y.*, Mao, Z. W.* Aquation and dimerization of osmium(II) anticancer complexes: a density functional theory study. Rsc Advances 2012, 2(2), 436-446. IF: 3.289
23. ? Li, J. M., Wang, Y. Y., Zhao, M. X., Tan, C. P., Li, Y. Q., Le, X. Y., Ji, L. N., Mao, Z. W.* Multifunctional QD-based co-delivery of siRNA and doxorubicin to HeLa cells for reversal of multidrug resistance and real-time tracking. Biomaterials 2012, 33(9), 2780-2790. IF: 8.387
201124. ?Tan, C. P., Wu, S. H., Lai, S. S., Wang, M. X., Chen, Y., Zhou, L. J., Zhu, Y. P., Lian, W., Peng, W. L., Ji, L. N., Xu, A. L.* Synthesis, structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-Norharman complexes. Dalton Transactions 2011, 40(34), 8611-8621. IF: 4.177
25. ?Tan, C. P., Hu, S., Liu, J.*, Ji, L. N.* Synthesis, characterization, antiproliferative and anti-metastatic properties of two ruthenium-DMSO complexes containing 2,2’-biimidazole. European Journal of Medicinal Chemistry 2011, 46(5), 1555-1563. IF: 3.902
26. ? Zhao, M. X., Li, J. M., Du, L. Y., Tan, C. P., Xia, Q.*, Mao, Z. W.*, Ji, L. N. Targeted cellular uptake and sirna silencing by quantum-dot nanoparticles coated with beta-cyclodextrin coupled to amino acids. Chemistry-A European Journal 2011, 17(18), 5171-5179. IF: 5.771
27. ? Li, J. M., Zhao, M. X., Su, H., Wang, Y. Y., Tan, C. P., Ji, L. N., Mao, Z. W.* Multifunctional quantum-dot-based siRNA delivery for HPV18 E6 gene silence and intracellular imaging. Biomaterials 2011, 32(31), 7978-
7987. IF: 8.387
2003-201028. ? Tan, C. P., Lai, S. S., Wu, S. H., Hu, S., Zhou, L. J., Chen, Y., Wang, M. X., Zhu, Y. P., Lian, W., Peng, W. L., Ji, L. N., Xu, A. L.* Nuclear permeable ruthenium(II) beta-carboline complexes induce autophagy to antagonize mitochondrial-mediated apoptosis. Journal of Medicinal Chemistry 2010, 53(21), 7613-7624. IF: 5.589
29. ? Tan, C. P., Liu, J.*, Li, H., Zheng, W. J., Shi, S., Chen, L. M., Ji, L. N.* Differences in structure, physiological stability, electrochemistry, cytotoxicity, DNA and protein binding properties between two Ru(III) complexes. Journal of Inorganic Biochemistry 2008, 102(2), 347-358. IF: 3.205
30. ? Tan, C. P., Liu, J.*, Chen, L. M., Shi, S., Ji, L. N.* Synthesis, structural characteristics, DNA binding properties and cytotoxicity studies of a series of Ru(III) complexes. Journal of Inorganic Biochemistry 2008, 102(8), 1644-1653. IF: 3.205
31. ? Liu, Y. N., Shi, S., Mei, W. J., Tan, C. P., Chen, L. M., Liu, J.*, Zheng, W. J.*, Ji, L. N. In vitro and in vivo investigations on the antiviral activity of a series of mixed-valence rare earth borotungstate heteropoly blues. European Journal of Medicinal Chemistry 2008, 43(9), 1963-1970. IF: 3.902
32. ? Liu, J.*, Zheng, W. J.*, Shi, S., Tan, C. P., Chen, J. C., Zheng, K. C., Ji, L. N. Synthesis, antitumor activity and structure-activity relationships of a series of Ru(II) complexes. Journal of Inorganic Biochemistry 2008, 102(2), 193-202. IF: 3.205
33. ? Chen, L. M., Liu, J.*, Chen, J. C., Tan, C. P., Shi, S., Zheng, K. C., Ji, L. N.* Synthesis, characterization, DNA-binding and spectral properties of complexes [Ru(L)(4)(dppz)](2+) (L = Im and MeIm). Journal of Inorganic Biochemistry 2008, 102(2), 330-341. IF: 3.205
34. ? Chen, L. M., Liu, J.*, Chen, J. C., Shi, S., Tan, C. P., Zheng, K. C., Ji, L. N.* Experimental and theoretical studies on the DNA-binding and spectral properties of water-soluble complex [Ru(MeIm)(4)(dpq)](2+). Journal of Molecular Structure 2008, 881(1-3), 156-166. IF: 1.78
35. ? Shi, S., Liu, J.*, Li, J., Zheng, K. C., Huang, X. M., Tan, C. P., Chen, L. M., Ji, L. N.* Synthesis, characterization and DNA-binding of novel chiral complexes Delta- and Lambda-[Ru(bpy)(2)L](2+) (L = o-mopip and p-mopip). Journal of Inorganic Biochemistry 2006, 100(3), 385-395. IF: 3.205
36. ? Shi, S., Liu, J.*, Li, J., Zheng, K. C., Tan, C. P., Chen, L. M., Ji, L. N.* Electronic effect of different positions of the -NO2 group on the DNA-intercalator of chiral complexes [Ru(bpy)(2)L](2+) (L = o-npip, m-npip and p-npip). Dalton Transactions 2005, 11), 2038-2046. IF: 4.177
37. ? Liu, J.*, Mei, W. J., Xu, A. W., Tan, C. P., Shi, S., Ji, L. N. Synthesis, characterization and antiviral activity against influenza virus of a series of novel manganese-substituted rare earth borotungstates heteropolyoxometalates. Antiviral Research 2004, 62(1), 65-71. IF: 4.909
38. ? Liu, J.*, Mei, W. J., Xu, A. W., Tan, C. P., Ji, L. N. Synthesis, characterization and antiviral activity of nickel-substituted rare earth molybdosilicic heteropoly blues. Transition Metal Chemistry 2003, 28(5), 500-505. IF: 1.465
